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cdb483ef JR |
1 | Summary: Model-based Analysis for ChIP-Seq |
2 | #Summary(pl.UTF-8): - | |
3 | Name: MACS | |
4 | Version: 1.4.1 | |
5 | Release: 1 | |
6 | License: Artistic | |
7 | Group: Development/Languages/Python | |
8 | # user and password are "publicly" visible on the web page (ROT13) | |
9 | Source0: http://macs:chipseq@liulab.dfci.harvard.edu/MACS/src/%{name}-%{version}.tar.gz | |
10 | # Source0-md5: 0b6490e37265d485e387b8323e810d3d | |
11 | URL: http://liulab.dfci.harvard.edu/MACS/ | |
12 | BuildRequires: python-distribute | |
13 | BuildRequires: rpm-pythonprov | |
ccdb66c6 | 14 | BuildRequires: rpmbuild(macros) >= 1.710 |
cdb483ef JR |
15 | Requires: python-modules |
16 | BuildArch: noarch | |
17 | BuildRoot: %{tmpdir}/%{name}-%{version}-root-%(id -u -n) | |
18 | ||
19 | %description | |
20 | Next generation parallel sequencing technologies made chromatin | |
21 | immunoprecipitation followed by sequencing (ChIP-Seq) a popular | |
22 | strategy to study genome-wide protein-DNA interactions, while | |
23 | creating challenges for analysis algorithms. We present Model-based | |
24 | Analysis of ChIP-Seq (MACS) on short reads sequencers such as Genome | |
25 | Analyzer (Illumina / Solexa). MACS empirically models the length of | |
26 | the sequenced ChIP fragments, which tends to be shorter than | |
27 | sonication or library construction size estimates, and uses it | |
28 | to improve the spatial resolution of predicted binding sites. | |
29 | MACS also uses a dynamic Poisson distribution to effectively capture | |
30 | local biases in the genome sequence, allowing for more sensitive and | |
31 | robust prediction. MACS compares favorably to existing ChIP-Seq | |
32 | peak-finding algorithms, is publicly available open source, and can be | |
33 | used for ChIP-Seq with or without control samples. | |
34 | ||
35 | #%description -l pl.UTF-8 | |
36 | ||
37 | %prep | |
38 | %setup -q | |
39 | ||
40 | # fix #!/usr/bin/env python -> #!/usr/bin/python: | |
41 | %{__sed} -i -e '1s,^#!.*python,#!%{__python},' bin/* setup.py | |
42 | ||
43 | %build | |
56d39876 | 44 | %py_build |
cdb483ef JR |
45 | |
46 | %install | |
47 | rm -rf $RPM_BUILD_ROOT | |
56d39876 | 48 | %py_install |
cdb483ef JR |
49 | |
50 | %py_ocomp $RPM_BUILD_ROOT%{py_sitescriptdir} | |
51 | %py_comp $RPM_BUILD_ROOT%{py_sitescriptdir} | |
52 | %py_postclean | |
53 | ||
54 | %clean | |
55 | rm -rf $RPM_BUILD_ROOT | |
56 | ||
57 | %files | |
58 | %defattr(644,root,root,755) | |
59 | %doc ChangeLog NEW_IN_MACS14 README | |
60 | %attr(755,root,root) %{_bindir}/* | |
61 | %dir %{py_sitescriptdir}/MACS14 | |
62 | %dir %{py_sitescriptdir}/MACS14/IO | |
63 | %{py_sitescriptdir}/MACS14/*.py[co] | |
64 | %{py_sitescriptdir}/MACS14/IO/*.py[co] | |
65 | %if "%{py_ver}" > "2.4" | |
66 | %{py_sitescriptdir}/MACS-*.egg-info | |
67 | %endif |