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1Summary: Model-based Analysis for ChIP-Seq
2#Summary(pl.UTF-8): -
3Name: MACS
4Version: 1.4.1
5Release: 1
6License: Artistic
7Group: Development/Languages/Python
8# user and password are "publicly" visible on the web page (ROT13)
9Source0: http://macs:chipseq@liulab.dfci.harvard.edu/MACS/src/%{name}-%{version}.tar.gz
10# Source0-md5: 0b6490e37265d485e387b8323e810d3d
11URL: http://liulab.dfci.harvard.edu/MACS/
12BuildRequires: python-distribute
13BuildRequires: rpm-pythonprov
ccdb66c6 14BuildRequires: rpmbuild(macros) >= 1.710
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15Requires: python-modules
16BuildArch: noarch
17BuildRoot: %{tmpdir}/%{name}-%{version}-root-%(id -u -n)
18
19%description
20Next generation parallel sequencing technologies made chromatin
21immunoprecipitation followed by sequencing (ChIP-Seq) a popular
22strategy to study genome-wide protein-DNA interactions, while
23creating challenges for analysis algorithms. We present Model-based
24Analysis of ChIP-Seq (MACS) on short reads sequencers such as Genome
25Analyzer (Illumina / Solexa). MACS empirically models the length of
26the sequenced ChIP fragments, which tends to be shorter than
27sonication or library construction size estimates, and uses it
28to improve the spatial resolution of predicted binding sites.
29MACS also uses a dynamic Poisson distribution to effectively capture
30local biases in the genome sequence, allowing for more sensitive and
31robust prediction. MACS compares favorably to existing ChIP-Seq
32peak-finding algorithms, is publicly available open source, and can be
33used for ChIP-Seq with or without control samples.
34
35#%description -l pl.UTF-8
36
37%prep
38%setup -q
39
40# fix #!/usr/bin/env python -> #!/usr/bin/python:
41%{__sed} -i -e '1s,^#!.*python,#!%{__python},' bin/* setup.py
42
43%build
56d39876 44%py_build
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45
46%install
47rm -rf $RPM_BUILD_ROOT
56d39876 48%py_install
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49
50%py_ocomp $RPM_BUILD_ROOT%{py_sitescriptdir}
51%py_comp $RPM_BUILD_ROOT%{py_sitescriptdir}
52%py_postclean
53
54%clean
55rm -rf $RPM_BUILD_ROOT
56
57%files
58%defattr(644,root,root,755)
59%doc ChangeLog NEW_IN_MACS14 README
60%attr(755,root,root) %{_bindir}/*
61%dir %{py_sitescriptdir}/MACS14
62%dir %{py_sitescriptdir}/MACS14/IO
63%{py_sitescriptdir}/MACS14/*.py[co]
64%{py_sitescriptdir}/MACS14/IO/*.py[co]
65%if "%{py_ver}" > "2.4"
66%{py_sitescriptdir}/MACS-*.egg-info
67%endif
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